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Articles (146)
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Mechanisms of signalling and biased agonism in G protein-coupled receptors

Wootten, Denise, Christopoulos, Arthur, Marti-Solano, Maria, Babu, M. Madan, Sexton, Patrick M.

Journal:

Nature Reviews Molecular Cell Biology

Année:

2018

Langue:

english

Fichier:

PDF, 6.08 MB

english, 2018

Studies on antimicrobial and wound healing applications of gauze coated with CHX–Ag hybrid NPs

Viswanathan, Kaliyaperumal, Bharathi, Babu Diviya, Karuppannan, Chitra, Sanjeevi, Thiyagarajan, Nithiyanantham, Madan, Arul Kumar, Kandasamy, Murugaiyan, Latha Mala Priyadhershini, Gopal, Dhinakarraj,

Journal:

IET Nanobiotechnology

Année:

2020

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2020

Robust One-Way ANOVA under Possibly Non-Regular Conditions

Gutti Jogesh Babu, A. R. Padmanabhan, Madan L. Puri

Journal:

Biometrical Journal

Année:

1999

Langue:

english

Fichier:

PDF, 231 KB

english, 1999

Subunit-selective N-terminal domain associations organize the formation of AMPA receptor heteromers

Penn, Andrew C, Veprintsev, Dmitry B, Babu, M Madan, Greger, Ingo H, Rossmann, Maxim, Sukumaran, Madhav

Journal:

The EMBO Journal

Année:

2011

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2011

Nanobiotechnology: Scaling up synthetic gene circuits

Chalancon, Guilhem, Babu, M. Madan

Journal:

Nature Nanotechnology

Année:

2010

Langue:

english

Fichier:

PDF, 265 KB

english, 2010

Molecular signatures of G-protein-coupled receptors

Venkatakrishnan, A. J., Deupi, Xavier, Lebon, Guillaume, Tate, Christopher G., Schertler, Gebhard F., Babu, M. Madan

Journal:

Nature

Année:

2013

Langue:

english

Fichier:

PDF, 2.16 MB

english, 2013

Vitrification of human 8-cell embryos, a modified protocol for better pregnancy rates

Gottumukkala Achyuta Rama Raju, Geddam Babu Haranath, Kota Murali Krishna, Gomedhikam Jaya Prakash, Kalagara Madan

Journal:

Reproductive BioMedicine Online

Année:

2005

Langue:

english

Fichier:

PDF, 214 KB

english, 2005

Controlling entropy to tune the functions of intrinsically disordered regions

Flock, Tilman, Weatheritt, Robert J, Latysheva, Natasha S, Babu, M Madan

Journal:

Current Opinion in Structural Biology

Année:

2014

Langue:

english

Fichier:

PDF, 1.39 MB

english, 2014

Genomic analysis reveals a tight link between transcription factor dynamics and regulatory network architecture

Jothi, Raja, Balaji, S, Wuster, Arthur, Grochow, Joshua A, Gsponer, Jörg, Przytycka, Teresa M, Aravind, L, Babu, M Madan

Journal:

Molecular Systems Biology

Année:

2009

Langue:

english

Fichier:

PDF, 2.58 MB

english, 2009

Patterns of Subnet Usage Reveal Distinct Scales of Regulation in the Transcriptional Regulatory Network of Escherichia coli

Marr, Carsten, Theis, Fabian J., Liebovitch, Larry S., Hütt, Marc-Thorsten, Babu, M. Madan

Journal:

PLoS Computational Biology

Année:

2010

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2010

Micronutrient Enrichment Mediated by Plant-Microbe Interactions and Rice Cultivation Practices

Adak, Anurup, Prasanna, Radha, Babu, Santosh, Bidyarani, Ngangom, Verma, Shikha, Pal, Madan, Shivay, Yashbir Singh, Nain, Lata

Journal:

Journal of Plant Nutrition

Année:

2016

Langue:

english

Fichier:

PDF, 612 KB

english, 2016

Structure, evolution and dynamics of transcriptional regulatory networks

Babu, M. Madan

Journal:

Biochemical Society Transactions

Année:

2010

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2010

Simultaneous quantification of protein order and disorder

Sormanni, Pietro, Piovesan, Damiano, Heller, Gabriella T, Bonomi, Massimiliano, Kukic, Predrag, Camilloni, Carlo, Fuxreiter, Monika, Dosztanyi, Zsuzsanna, Pappu, Rohit V, Babu, M Madan, Longhi, Sonia,

Journal:

Nature Chemical Biology

Année:

2017

Langue:

english

Fichier:

PDF, 2.51 MB

english, 2017

Human Diseases from Gain-of-Function Mutations in Disordered Protein Regions

Li, Xiao-Han, Babu, M. Madan

Journal:

Cell

Année:

2018

Langue:

english

Fichier:

PDF, 536 KB

english, 2018

From prioritisation to understanding: mechanistic predictions of variant effects

Slodkowicz, Greg, Babu, M Madan

Journal:

Molecular Systems Biology

Année:

2018

Fichier:

PDF, 236 KB

2018

Evolution of eukaryotic genome architecture: Insights from the study of a rapidly evolving metazoan, Oikopleura dioica : Non-adaptive forces such as elevated mutation rates may influence the evolution of genome architecture

Sreenivas Chavali, David A. de Lima Morais, Julian Gough, M. Madan Babu

Journal:

BioEssays

Année:

2011

Langue:

english

Fichier:

PDF, 717 KB

english, 2011

The discovery and structure–activity relationships of 2-(piperidin-3-yl)-1H-benzimidazoles as selective, CNS penetrating H1-antihistamines for insomnia

Karine Lavrador-Erb, Satheesh Babu Ravula, Jinghua Yu, Said Zamani-Kord, Wilna J. Moree, Robert E. Petroski, Jianyun Wen, Siobhan Malany, Samuel R.J. Hoare, Ajay Madan, Paul D. Crowe, Graham Beaton

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2010

Langue:

english

Fichier:

PDF, 710 KB

english, 2010

Registering α-helices and β-strands using backbone CH…O interactions

S. Kumar Singh, M. Madan Babu, P. Balaram

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2003

Langue:

english

Fichier:

PDF, 166 KB

english, 2003

Exploring the environmental preference of weak interactions in (α/β)8 barrel proteins

S. Chakkaravarthi, M. Madan Babu, M. Michael Gromiha, G. Jayaraman, R. Sethumadhavan

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2006

Langue:

english

Fichier:

PDF, 379 KB

english, 2006

TAT-Pathway-Dependent Lipoproteins as a Niche-Based Adaptation in Prokaryotes

Hamsanathan Shruthi, Mohan Madan Babu, Krishnan Sankaran

Journal:

Journal of Molecular Evolution

Année:

2010

Langue:

english

Fichier:

PDF, 561 KB

english, 2010

Synthesis and biological evaluation of [4-(2-phenylethenesulfonylmethyl)phenyl]-quinazolin-4-yl-amines as orally active anti-cancer agents

Vedula M. Sharma, K.V. Adi Seshu, V. Chandra Sekhar, Sachin Madan, B. Vishnu, P.Aravind Babu, C. Vamsee Krishna, J. Sreenu, V. Ravi Krishna, A. Venkateswarlu, Sriram Rajagopal, R. Ajaykumar, T.Sravan

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2004

Langue:

english

Fichier:

PDF, 247 KB

english, 2004

The efficiency of mitochondrial electron transport chain is increased in the long-lived mrg19 Saccharomyces cerevisiae

Nitish Mittal, M. Madan Babu, Nilanjan Roy

Journal:

Aging Cell

Année:

2009

Langue:

english

Fichier:

PDF, 309 KB

english, 2009

Genomic analysis of regulatory network dynamics reveals large topological changes

Luscombe, Nicholas M., Madan Babu, M., Yu, Haiyuan, Snyder, Michael, Teichmann, Sarah A., Gerstein, Mark

Journal:

Nature

Année:

2004

Langue:

english

Fichier:

PDF, 404 KB

english, 2004

Gene regulatory network growth by duplication

Teichmann, Sarah A, Babu, M Madan

Journal:

Nature Genetics

Année:

2004

Langue:

english

Fichier:

PDF, 747 KB

english, 2004

Evolving nature of the AP2 α-appendage hub during clathrin-coated vesicle endocytosis

Praefcke, Gerrit J K, Ford, Marijn G J, Schmid, Eva M, Olesen, Lene E, Gallop, Jennifer L, Peak-Chew, Sew-Yeu, Vallis, Yvonne, Babu, M Madan, Mills, Ian G, McMahon, Harvey T

Journal:

The EMBO Journal

Année:

2004

Langue:

english

Fichier:

PDF, 590 KB

english, 2004

Microwave extraction and rapid isolation of arjunic acid from Terminalia arjuna (Roxb. ex DC.) stem bark and quantification of arjunic acid and arjunolic acid using HPLC-PDA technique

Subash Chandra Verma, Chhoten Lal Jain, Madan Mohan Padhi, Ramesh Babu Devalla

Journal:

Journal of Separation Science

Année:

2012

Langue:

english

Fichier:

PDF, 625 KB

english, 2012

Lead optimization of 2-(piperidin-3-yl)-1H-benzimidazoles: Identification of 2-morpholin- and 2-thiomorpholin-2-yl-1H-benzimidazoles as selective and CNS penetrating H1-antihistamines for insomnia

Satheesh Babu Ravula, Jinghua Yu, Joe A. Tran, Melissa Arellano, Fabio C. Tucci, Wilna J. Moree, Bin-Feng Li, Robert E. Petroski, Jianyun Wen, Siobhan Malany, Samuel R.J. Hoare, Ajay Madan, Paul D. Cr

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 872 KB

english, 2012

Genomic neighbourhood and the regulation of gene expression

Subhajyoti De, M Madan Babu

Journal:

Current Opinion in Cell Biology

Année:

2010

Langue:

english

Fichier:

PDF, 269 KB

english, 2010

Duel of the fates: the role of transcriptional circuits and noise in CD4+ cells

Daniel Hebenstreit, Andrew Deonarine, M Madan Babu, Sarah A Teichmann

Journal:

Current Opinion in Cell Biology

Année:

2012

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2012

The rules of disorder or why disorder rules

Jörg Gsponer, M. Madan Babu

Journal:

Progress in Biophysics and Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 266 KB

english, 2009

Structure and evolution of transcriptional regulatory networks

M Madan Babu, Nicholas M Luscombe, L Aravind, Mark Gerstein, Sarah A Teichmann

Journal:

Current Opinion in Structural Biology

Année:

2004

Langue:

english

Fichier:

PDF, 911 KB

english, 2004

Intrinsically disordered proteins: regulation and disease

M Madan Babu, Robin van der Lee, Natalia Sanchez de Groot, Jörg Gsponer

Journal:

Current Opinion in Structural Biology

Année:

2011

Langue:

english

Fichier:

PDF, 502 KB

english, 2011

Recognition Pliability Is Coupled to Structural Heterogeneity: A Calmodulin Intrinsically Disordered Binding Region Complex

Malini Nagulapalli, Giacomo Parigi, Jing Yuan, Joerg Gsponer, George Deraos, Vladimir V. Bamm, George Harauz, John Matsoukas, Maurits R.R. de Planque, Ioannis P. Gerothanassis, M. Madan Babu, Claudio

Journal:

Structure

Année:

2012

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2012

GenCompass: a universal system for analysing gene expression for any genome

Nicholas M. Luscombe, M. Madan Babu

Journal:

Trends in Biotechnology

Année:

2004

Langue:

english

Fichier:

PDF, 261 KB

english, 2004

Chemogenomics and biotechnology

Arthur Wuster, M. Madan Babu

Journal:

Trends in Biotechnology

Année:

2008

Langue:

english

Fichier:

PDF, 567 KB

english, 2008

Comparison of transcription regulatory interactions inferred from high-throughput methods: what do they reveal?

S. Balaji, Lakshminarayan M. Iyer, M. Madan Babu, L. Aravind

Journal:

Trends in Genetics

Année:

2008

Langue:

english

Fichier:

PDF, 455 KB

english, 2008

Interplay between gene expression noise and regulatory network architecture

Guilhem Chalancon, Charles N.J. Ravarani, S. Balaji, Alfonso Martinez-Arias, L. Aravind, Raja Jothi, M. Madan Babu

Journal:

Trends in Genetics

Année:

2012

Langue:

english

Fichier:

PDF, 3.08 MB

english, 2012

Conservation of gene co-regulation in prokaryotes and eukaryotes

Sarah A Teichmann, M.Madan Babu

Journal:

Trends in Biotechnology

Année:

2002

Langue:

english

Fichier:

PDF, 41 KB

english, 2002

Functional determinants of transcription factors in Escherichia coli: protein families and binding sites

M Madan Babu, Sarah A Teichmann

Journal:

Trends in Genetics

Année:

2003

Langue:

english

Fichier:

PDF, 303 KB

english, 2003

Exploiting gene deletion fitness effects in yeast to understand the modular architecture of protein complexes under different growth conditions

Roland A Pache, M Madan Babu, Patrick Aloy

Journal:

BMC Systems Biology

Année:

2009

Langue:

english

Fichier:

PDF, 581 KB

english, 2009

Dissecting ensemble networks in ES cell populations reveals micro-heterogeneity underlying pluripotency

Trott, Jamie, Hayashi, Katsuhiko, Surani, Azim, Babu, M. Madan, Martinez-Arias, Alfonso

Journal:

Molecular BioSystems

Année:

2012

Langue:

english

Fichier:

PDF, 2.85 MB

english, 2012

Evidence of a bigenomic regulation of mitochondrial gene expression by thyroid hormone during rat brain development

Rohit Anthony Sinha, Amrita Pathak, Vishwa Mohan, Satish Babu, Amit Pal, Drirh Khare, Madan M. Godbole

Journal:

Biochemical and Biophysical Research Communications

Année:

2010

Langue:

english

Fichier:

PDF, 362 KB

english, 2010

Eukaryotic gene regulation in three dimensions and its impact on genome evolution

M Madan Babu, Sarath Chandra Janga, Ines de Santiago, Ana Pombo

Journal:

Current Opinion in Genetics & Development

Année:

2008

Langue:

english

Fichier:

PDF, 647 KB

english, 2008

Evolutionary Dynamics of Prokaryotic Transcriptional Regulatory Networks

M. Madan Babu, Sarah A. Teichmann, L. Aravind

Journal:

Journal of Molecular Biology

Année:

2006

Langue:

english

Fichier:

PDF, 1.74 MB

english, 2006

Uncovering a Hidden Distributed Architecture Behind Scale-free Transcriptional Regulatory Networks

S. Balaji, Lakshminarayan M. Iyer, L. Aravind, M. Madan Babu

Journal:

Journal of Molecular Biology

Année:

2006

Langue:

english

Fichier:

PDF, 463 KB

english, 2006

Comprehensive Analysis of Combinatorial Regulation using the Transcriptional Regulatory Network of Yeast

S. Balaji, M. Madan Babu, Lakshminarayan M. Iyer, Nicholas M. Luscombe, L. Aravind

Journal:

Journal of Molecular Biology

Année:

2006

Langue:

english

Fichier:

PDF, 770 KB

english, 2006

Interplay Between Network Structures, Regulatory Modes and Sensing Mechanisms of Transcription Factors in the Transcriptional Regulatory Network of E. coli

S. Balaji, M. Madan Babu, L. Aravind

Journal:

Journal of Molecular Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2007

Mechanistic Insight into Site-Restricted Monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI

Arno F. Alpi, Paul E. Pace, M. Madan Babu, Ketan J. Patel

Journal:

Molecular Cell

Année:

2008

Langue:

english

Fichier:

PDF, 1.66 MB

english, 2008

Tissue-Specific Splicing of Disordered Segments that Embed Binding Motifs Rewires Protein Interaction Networks

Marija Buljan, Guilhem Chalancon, Sebastian Eustermann, Gunter P. Wagner, Monika Fuxreiter, Alex Bateman, M. Madan Babu

Journal:

Molecular Cell

Année:

2012

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2012

DNA Sequence Preferences of Transcriptional Activators Correlate More Strongly than Repressors with Nucleosomes

Varodom Charoensawan, Sarath Chandra Janga, Martha L. Bulyk, M. Madan Babu, Sarah A. Teichmann

Journal:

Molecular Cell

Année:

2012

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2012